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GLP-1 RAs might be useful for the treatment of people with T2DM and overweight/obesity, since they have been shown to be beneficial in achieving weight loss targets, an essential component of the therapeutic strategy of T2DM [3]

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As discussed above, lipopolysaccharides (LPS) could prompt inflammation and amyloidogenesis in the brain, by inducing the disorder of TNF-a, IL-1ฮฒ, and cyclooxygenase-2 (COX-2) (87)

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